The opioid epidemic continues to ravage communities across the CSG South region. According to the U.S. Centers for Disease Control and Prevention (CDC), from 2019 to 2020, opioid-involved death rates increased by 38 percent. While there have been efforts around the prescription and legal side of opioids, fentanyl and its derivatives are causing even further harm to communities. Due to its potency (roughly 100x more potent than morphine) and the ease with which it can be synthesized, fentanyl is becoming more prevalent, and increasingly is being mixed with other substances, often to deadly effect. From 2019 to 2020, the CDC found that synthetic opioid-involved death rates increased by 56 percent. What legal and criminal justice policies can states employ to attack the supply side of the problem? What can states do from the human services side to prevent deaths and assist those seeking recovery? Participants in this Masterclass will learn about successful policies undertaken in other states and engage with subject-matter experts on emerging solutions.